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Estrogen, Aromatase & Insulin

Posted at 11:10 PM on August 25, 2009


The older the male, the greater the possibility of elevated aromatase enzyme expression.  Enlarged prostate, balding, insulin resistance, enlarged breasts, abdominal obesity have a common link, which is excess aromatization.  Many men who are checked for low testosterone and then are subsequently given testosterone shots, creams or gel may not get much better unless their aromatization expression is checked. 


What good is testosterone supplementation if most of it is being converted into estrogen?  More importantly, how does one check for this?  The answer is testosterone to estrogen ratio.


Looking at your lab tests, make note if your testosterone is below the mid-range while also checking to see if your estrogen is above the mid-range.  The degree of concern of course is how close to the low end range is testosterone relative to how close the estrogen level is toward the top of its range.  If this tendency is shown, elevated aromatization is likely present.  Furthermore, and with a high confidence level you're also insulin resistant. 


What to do?  Identify your nutritional or metabolic type, but regardless of this, laying off refined grains, starches, sugars, vegetable oils, hydrogenated oils, pre-packaged foods is a step in the right direction.  Next, improving glucose metabolism and optimizing a balance of healthy gut microflora is very important.  Checking your thyroid and/or iodine intake.   Some of estrogen's adverse effects can be contained with sufficent iodine intake.  Heightened levels of estrogen can increase prolactin and also induce hypothyroidism.  Beware of anti-anxiety and anti-depressant medication, since many of these increase prolactin levels, and suppress the thyroid all leading to increased estrogen levels.


Supplements for this would include, a very good probiotic, Spruce Lignans (7-hydroxymatairesinol), iodine, Curcumin, Lipoic Acid, Ecklonia Cava, Resveratrol, Zinc, Omega-3 fatty acids, Nettle using the methanolic extract only, and passionflower.


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