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Topical Lithium Orotate & DMSO

DMSO boosts Wnt signaling and increases levels of beta-catenin.  

DMSO is a co-factor with Lithium Orotate, as Lithium downregulates glycogen synthase kinase-3beta (GSK-3b).  GSK-3b inhibits the activity of the Wnt pathway.  Lithium suppresses GSK-3b, allowing an increase in Wnt signaling via DSMO.  Moreover, GSK-3b upregulates the apoptoic protein Bcl-2, while Lithium reduces Bcl-2 and upregulates Bax, sparing cells and reducing sebum.

Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice

PNAS | November 29, 2005 | vol. 102 | no. 48 | 17406-17411

Per 8 oz. bottle of non-SLS shampoo, I use the following:

1 & 1/2 teaspoons to 2 teaspoons of crushed Lithium pills (or powder)

1 tsp of DMSO liquid (99%)  Note:  If you have sensitive skin use a 50 to 70% solution.

Where to buy:

DMSO liquid 99% click here

crushed Lithium pills (or powder) type in "lithium" in the search box click here

Non-SLS shampoo?   I use this one if you woud like to try it  click here

Patent that inspired this formula: click here

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